Monsanto's Worst Fear May Be Coming True


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Categories: Health & Nutrition

Why the pressure to remove GMOs will grow

The other factor in all this turmoil is that the GMO technology wheel has not stopped turning. New GMO products are coming on stream that will likely make crop biotechnology even less popular than it is now. This will further ramp up the pressure on brands and stores to go GMO-free. There are several contributory factors.

The first issue follows from the recent US approvals of GMO crops resistant to the herbicides 2,4-D and Dicamba. These traits are billed as replacements for Roundup-resistant traits whose effectiveness has declined due to the spread of weeds resistant to Roundup (Glyphosate).

The causes of the problem, however, lie in the technology itself. The introduction of Roundup-resistant traits in corn and soybeans led to increasing Roundup use by farmers (Benbrook 2012). Increasing Roundup use led to weed resistance, which led to further Roundup use, as farmers increased applications and dosages. This translated into escalated ecological damage and increasing residue levels in food. Roundup is now found in GMO soybeans intended for food use at levels that even Monsanto used to call “extreme” (Bøhn et al. 2014).

The two new herbicide-resistance traits are set to recapitulate this same story of increasing agrochemical use. But they will also amplify it significantly,

The specifics are worth considering. First, the spraying of 2,4-D and Dicamba on the newer herbicide-resistant crops will not eliminate the need for Roundup, whose use will not decline (see Figure).

Predicted herbicide use to 2025 (Mortensen et al 2012)

PREDICTED HERBICIDE USE TO 2025 (MORTENSEN ET AL 2012)

That is because, unlike Roundup, neither 2,4-D nor Dicamba are broad-spectrum herbicides. They will have to be sprayed together with Roundup, or with each other (or all of them together) to kill all weeds. This vital fact has not been widely appreciated.

Confirmation comes from the companies themselves. Monsanto is stacking (i.e. combining) Dicamba resistance with Roundup resistance in its Xtend crops and Dow isstacking 2,4-D resistance with Roundup resistance in its Enlist range. (Notably, resistance to other herbicides, such as glufosinate, are being stacked in all these GMO crops too.)

The second issue is that the combined spraying of 2,4-D and Dicamba and Roundup, will only temporarily ease the weed resistance issues faced by farmers. In the medium and longer terms, they will compound the problems. That is because new herbicide-resistant weeds will surely evolve. In fact, Dicamba-resistant and 2,4-D-resistant weeds already exist. Their spread, and the evolution of new ones, can be guaranteed (Mortensen et al 2012). This will bring greater profits for herbicide manufacturers, but it will also bring greater PR problems for GMOs and the food industry. GMO soybeans and corn will likely soon have “extreme levels” of at least three different herbicides, all of them with dubious safety records (Schinasi and Leon 2014).

The first time round, Monsanto and Syngenta’s PR snow-jobs successfully obscured this, not just from the general public, but even within agronomy. But it is unlikely they will be able to do so a second time. 2,4-D and Dicamba-resistant GMOs are thus a PR disaster waiting to happen.

 


A pipeline full of problems: risk and perception

The longer term problem for GMOs is that, despite extravagant claims, their product pipeline is not bulging with promising ideas. Mostly, it is more of the same: herbicide resistance and insect resistance.

The most revolutionary and innovative part of that pipeline is a technology and not a trait. Many products in the GMO pipeline are made using RNA interference technologies that rely on double-stranded RNAs (dsRNAs). dsRNA is a technology with two problems. One is that products made with it (such as the “Arctic” Apple, the “Innate” Potato, and Monsanto’s “Vistive Gold” Soybeans) are unproven in the field. Like its vanguard, a Brazilian virus-resistant bean, they may never work under actual farming conditions.

But if they do work, there is a clear problem with their safety which is explained in detail here (pdf).

In outline, the problem is this: the long dsRNA molecules needed for RNA interference were rejected long ago as being too hazardous for routine medical use (Anonymous, 1969). The scientific literature even calls them “toxins”, as in this paper title from 1969:

Absher M., and Stinebring W. (1969) Toxic properties of a synthetic double-stranded RNA. Nature 223: 715-717. (not online)

As further evidence of this, long dsRNAs are now used in medicine to cause autoimmune disorders in mice, in order to study these disorders (Okada et al 2005).

The Absher and Stinebring paper comes from a body of research built up many years ago, but its essential findings have been confirmed and extended by more modern research. We now know why dsRNAs cause harm. They trigger destructive anti-viral defence pathways in mammals and other vertebrates and there is a field of specialist research devoted to showing precisely how this damages individual cells, whole tissues, and results in auto-immune disease in mice (Karpala et al. 2005).

The conclusion therefore, is that dsRNAs that are apparently indistinguishable from those produced in, for example, the Arctic apple and Monsanto’s Vistive Gold Soybean, have strong negative effects on vertebrate animals (but not plants). These vertebrate effects are found even at low doses. Consumers are vertebrate animals. They may not appreciate the thought that their healthy fats and forever apples also contain proven toxins. And on a business front, consumer brands will not relish defending dsRNA technology once they understand the reality. They may not wish to find themselvesdefending the indefensible.

The bottom line is this. Either dsRNAs will sicken or kill people, or, they will give opponents of biotechnology plenty of ammunition. The scientific evidence, as it currently stands, suggests they will do both. dsRNAs, therefore, are a potentially huge liability.

The last pipeline problem stems from the first two. The agbiotech industry has long held out the prospect of “consumer benefits” from GMOs. Consumer benefits (in the case of food) are most likely to be health benefits (improved nutrition, altered fat composition, etc.). The problem is that the demographic of health-conscious consumers no doubt overlaps significantly with the demographic of those most wary of GMOs. Show a consumer a “healthy GMO” and they are likely to show you an oxymoron. The likely health market in the US for customers willing to pay more for a GMO has probably evaporated in the last few years as GMOs have become a hot public issue.

The end-game for GMOs?



The traditional chemical industry approach to such a problem is a familiar repertoire of intimidation and public relations. Fifty years ago, the chemical industry outwitted and outmanoeuvered environmentalists after the death of Rachel Carson (see the books Toxic Sludge is Good for You andTrust Us We’re Experts). But that was before email, open access scientific publication, and the internet. Monsanto and its allies have steadily lost ground in a world of peer-to-peer communication. GMOs have become a liability, despite their best efforts.

The historic situation is this: in any country, public acceptance of GMOs has always been based on lack of awareness of their existence. Once that ignorance evaporates and the scientific and social realities start to be discussed, ignorance cannot be reinstated. From then on the situation moves into a different, and much more difficult phase for the defenders of GMOs.

Nevertheless, in the US, those defenders have not yet given up. Anyone who keeps up with GMOs in the media knows that the public is being subjected to an unrelenting and concerted global blitzkrieg.

Pro-GMO advocates and paid-for journalists, presumably financed by the life-science industry, sometimes fronted by non-profits such as the Bill and Melinda Gates Foundation, are being given acres of prominent space to make their case. Liberal media outlets such as the New York Times, theNational GeographicThe New YorkerGrist magazine, theObserver newspaper, and any others who will have them (which is most) have been deployed to spread its memes. Cornell University has meanwhile received a $5.6 million grant by the Gates Foundation to “depolarize” negative GMO publicity.

But so far there is little sign that the growth of anti-GMO sentiment in Monsanto’s home (US) market can be halted. The decision by Chipotle is certainly not an indication of faith that it can.

For Monsanto and GMOs the situation suddenly looks ominous. Chipotle may well represent the beginnings of a market swing of historic proportions. GMOs may be relegated to cattle-feed status, or even oblivion, in the USA. And if GMOs fail in the US, they are likely to fail elsewhere.


GMO roll-outs in other countries have relied on three things: the deep pockets of agribusinesses based in the United States, their political connections, and the notion that GMOs represent “progress”. If those three disappear in the United States, the power to force open foreign markets will disappear too. The GMO era might suddenly be over.

Via:  Eat Local Grown

Editors note: Click here to Find a Local Farmer

By Jonathan Latham, PhD

Commentary:  

Monsanto

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